Targeted Cancer Treatments

Targeted Cancer Treatments

Some targeted cancer treatments:

a. Cancer cells often overproduce proteins called growth factor receptors, which are found on the cells’ surface and are hence accessible to monoclonal antibodies. Sometimes these growth factor receptors are faulty and overactive.

b. Growth factor receptors trigger the activity of other proteins inside the cell, many of which are kinases that can be blocked with kinase inhibitors.

c. Blood cell cancers (e.g., leukemias and lymphomas) have many proteins on their surface known as CD antigens. Many CD antigens (e.g., CD20, CD38, and CD19) are the targets of antibody-based treatments for blood cancers.  Read More